WebDec 28, 2024 · A new method for the synthesis of α-trifluoromethylated tertiary alcohols bearing coumarins is described. The reaction of 3-(trifluoroacetyl)coumarin and pyrrole provided the target compounds with high yields under catalyst-free, mild conditions. The crystal structure of compound 3fa was investigated by X-ray diffraction analysis. The … WebPPh 3 ‑Catalyzed [3 + 2] Spiroannulation of 1C,3N‑Bisnucleophiles Derived from Secondary β‑Ketoamides with δ‑Acetoxy Allenoate: A Route to Functionalized Spiro …
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WebHu Jian; Wei Yabing and Tong, Xiaofeng*, Phosphine-Catalyzed [3+2]Annulations of gamma-Functionalized Butynoates and 1C,3O-Bisnucleophiles: HighlySelective … WebMay 27, 2024 · An oxidative [3+3] annulation of atropaldehyde acetals with various 1,3-bisnucleophiles was developed using either N-bromosuccinimide or copper(II) bromide as oxidizing reagent and Brønsted or Lewis acids as catalyst.The [3+3] annulations can be considered mechanistically as oxidizing reagent-induced acid-acid-catalyzed domino … bottomless brunch revolution bournemouth
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WebFeb 19, 2024 · A wide variety of bisnucleophiles can add across the α,β-unsaturated acylazoliums to form various five and six-membered heterocycles and carbocycles. Moreover, suitably substituted nucleophiles can add to this intermediate and result in valuable products following cascade processes. Employing chiral NHCs in the process … WebDec 1, 2005 · Reactions of acylimines of methyl trifluoropyruvate with C,N-bisnucleophiles gave fluoro-containing heterocycles including the 5-oxo-4,5-dihydro-1H-pyrrole fragment. Discover the world's research ... WebMay 30, 2024 · A straightforward access to tricyclic indoles bearing 3,4-fused seven-membered rings has been established by using 4-aminoindoles as 1,4-bisnucleophiles … hay seed levelsin farm heroes saga